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Poster Session I - NOVEL TARGET/ EXPERIMENTAL FIDINGS TO CLINICAL TRANSLATION 06.00 - NOVEL TARGET/ EXPERIMENTAL FIDINGS TO CLINICAL TRANSLATION - 06.01 - PATHOPHYSIOLOGY OF STROKE / TRANSLATIONAL MEDICINE P472 - ESOC25-1380 ASSOCIATION BETWEEN COGNITIVE FUNCTION AND CEREBROVASCULAR RESERVE: IMPACT OF HBA1C Mami Ishikawa 1,2 , Masashi Ikota 1 , Taku Uchiyama 1 , Heiji Naritaka 2 , Gen Kusaka 1 1 Saitama Medical Center, Jichi Medical University, Saitama, Japan, 2 Edogawa Hospital, Tokyo, Japan Background and Aims: Cognitive impairment has been reported in patients with steno-occlusive disease of a main cerebral artery without causative lesions on magnetic resonance imaging